Use of comprehensive recruitment strategies in the glycemia reduction approaches in diabetes: A comparative effectiveness study (GRADE) multi-center clinical trial.

ABSTRACT:

Background/aims

We present and describe recruitment strategies implemented from 2013 to 2017 across 45 clinical sites in the United States, participating in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study, an unmasked, randomized controlled trial evaluating four glucose-lowering medications added to metformin in individuals with type 2 diabetes mellitus (duration of diabetes <10 years). We examined the yield of participants recruited through Electronic Health Records systems compared to traditional recruitment methods to leverage access to type 2 diabetes patients in primary care.

Methods

Site selection criteria included availability of the study population, geographic representation, the ability to recruit and retain a diverse pool of partic

SUBMITTER: Cherrington AL 

PROVIDER: S-EPMC10524662 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature