Arterial spin labeled perfusion imaging with balanced steady-state free precession readout and radial sampling.

ABSTRACT:

Purpose

To develop an arterial spin labeling (ASL) perfusion imaging method with balanced steady-state free precession (bSSFP) readout and radial sampling for improved SNR and robustness to motion and off-resonance effects.

Methods

An ASL perfusion imaging method was developed with pseudo-continuous arterial spin labeling (pCASL) and bSSFP readout. Three-dimensional (3D) k-space data were collected in segmented acquisitions following a stack-of-stars sampling trajectory. Multiple phase-cycling technique was utilized to improve the robustness to off-resonance effects. Parallel imaging with sparsity-constrained image reconstruction was used to accelerate imaging or increase the spatial coverage.

Results

ASL with bSSFP readout showed higher spatial and temporal SNRs of t

SUBMITTER: Han PK 

PROVIDER: S-EPMC10524790 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature