Metabolism and pharmacokinetics of vitamin D in patients with cystic fibrosis.

ABSTRACT: Patients with cystic fibrosis (CF) commonly have lower circulating concentrations of 25-hydroxyvitamin D (25(OH)D) than healthy populations. We comprehensively compared measures of vitamin D metabolism among individuals with CF and healthy control subjects. In a cross-sectional study, serum from participants with CF (N = 83) and frequency-matched healthy control subjects by age and race (N = 82) were analyzed for: 25(OH)D₂ and 25(OH)D₃, 1α,25-dihydroxyvitamins D₂ and D₃ (1α,25(OH)₂D₂ and 1α,25(OH)₂D₃), 24,25-dihydroxyvitamin D₃ (24,25(OH)₂D₃), 4β,25-dihydroxyvitamin D₃ (4β,25(OH)₂D₃), 25-hydroxyvitamin D₃-3-sulfate (25(OH)D

SUBMITTER: Bergagnini-Kolev MC 

PROVIDER: S-EPMC10524963 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature