Evaluation of Bile Salts on the Survival and Modulation of Virulence of Aliarcobacter butzleri.

ABSTRACT: Aliarcobacter butzleri is a Gram-negative bacterium associated with infections of the gastrointestinal tract and widely distributed in various environments. For successful infection, A. butzleri should be able to tolerate various stresses during gastrointestinal passage, such as bile. Bile represents an antimicrobial host barrier that acts against external noxious agents and consists of a variety of bile salts. The intestinal bile salts act as detergents involved in the antimicrobial host defense; although, on the bacterial side, they could also serve as a signal to activate virulence mechanisms. The aim of this work was to understand the effects of bile salts on the survival and virulence of A. butzleri. In our study, A. butzleri was able to survive in the pres

SUBMITTER: Mateus C 

PROVIDER: S-EPMC10525121 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature