Effect of Diet and Oxidative Stress in the Pathogenesis of Lymphoproliferative Disorders.

ABSTRACT: Lymphomas are a heterogeneous group of pathologies that result from clonal proliferation of lymphocytes. They are classified into Hodgkin lymphoma and non-Hodgkin lymphoma; the latter develops as a result of B, T, or NK cells undergoing malignant transformation. It is believed that diet can modulate cellular redox state and that oxidative stress is implicated in lymphomagenesis by acting on several biological mechanisms; in fact, oxidative stress can generate a state of chronic inflammation through the activation of various transcription factors, thereby increasing the production of proinflammatory cytokines and causing overstimulation of B lymphocytes in the production of antibodies and possible alterations in cellular DNA. The purpose of our work is to investigate the results of in vitro

SUBMITTER: Cancemi G 

PROVIDER: S-EPMC10525385 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature