Streptomyces rugosispiralis sp. nov., a Novel Actinobacterium Isolated from Peat Swamp Forest Soil That Produces Ansamycin Derivatives and Nocardamines.

ABSTRACT: Actinomycetes, especially the genus Streptomyces, are one of the most promising sources of bioactive natural products. In this study, a novel Streptomyces strain, RCU-064^T, was isolated from a soil sample collected from a peat swamp forest in Thailand. Strain RCU-064^T showed the highest 16S rRNA gene sequence similarity (99.06%) with Streptomyces malaysiensis NBRC 16446^T. Based on a polyphasic approach, strain RCU-064^T represents a novel species of the genus Streptomyces, for which the name Streptomyces rugosispiralis sp. nov. is proposed. The chemical isolation of the crude ethyl acetate extracts of the strain led to the isolation of six compounds: (1) geldanamycin, (2) 17-O-demethylgeldana

SUBMITTER: Weeraphan T 

PROVIDER: S-EPMC10525797 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature