The Role of Blood Microbiome in the Development of Thyroid Cancer in Breast Cancer Survivors.

ABSTRACT: Patients diagnosed with breast cancer are likely to be diagnosed with thyroid cancer as a second primary cancer. Similarly, patients with thyroid cancer are likely to develop breast cancer. In this study, we found an association between these two types of cancers in the microbiomes of patients with breast cancer. Blood samples were collected from 96 patients with breast cancer, their bacterial extracellular vesicles were isolated, and their microbiomes were analyzed. After microbiome analysis, researchers performed thyroid function tests, estrogen levels, and thyroid ultrasound results of these patients, and the relationships among these parameters were analyzed. Based on the thyroid ultrasonography results, differences in the microbiome were confirmed in the normal, cyst, nodule, and thyr

SUBMITTER: An J 

PROVIDER: S-EPMC10526815 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature