Blood Pressure, Incident Cognitive Impairment, and Severity of CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.

ABSTRACT:

Rationale & objective

Hypertension is a known risk factor for dementia and cognitive impairment. There are limited data on the relation of systolic blood pressure (SBP) and diastolic blood pressure (DBP) with incident cognitive impairment in adults with chronic kidney disease. We sought to identify and characterize the relationship among blood pressure, cognitive impairment, and severity of decreased kidney function in adults with chronic kidney disease.

Study design

Longitudinal cohort study.

Setting & participants

3,768 participants in the Chronic Renal Insufficiency Cohort (CRIC) Study.

Exposure

Baseline SBP and DBP were examined as exposure variables, using continuous (linear, per 10-mm Hg higher), categorical (SBP<120 [reference], 120 to 140,>140mm Hg; DBP

SUBMITTER: Babroudi S 

PROVIDER: S-EPMC10526961 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature