Retrospective Analysis of Sugammadex Use in Adolescent Females on Progestin-Containing Contraceptives.

ABSTRACT:

Study objective

Sugammadex, a novel neuromuscular blockade reversal agent, functions as a steroid binder postulated to decrease hormone exposure used within progestin-containing contraceptive medications. Thus, alternative non-medication contraceptive methods are recommended to prevent unplanned pregnancies. The study aims were to evaluate sugammadex use in adolescent females prescribed a progestin-containing contraceptive and positive pregnancy screening frequency. We hypothesized that sugammadex use is infrequent in this population and no pregnancy screens would be positive.

Methods

This is a retrospective observational cohort study utilizing the TriNetX electronic health record database of female subjects aged 12-21 years reported to be prescribed sugammadex. The data col

SUBMITTER: Hodge C 

PROVIDER: S-EPMC10527360 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature