Fully automated construction of three-dimensional finite element simulations from Optical Coherence Tomography.

ABSTRACT: Despite recent advances in diagnosis and treatment, atherosclerotic coronary artery diseases remain a leading cause of death worldwide. Various imaging modalities and metrics can detect lesions and predict patients at risk; however, identifying unstable lesions is still difficult. Current techniques cannot fully capture the complex morphology-modulated mechanical responses that affect plaque stability, leading to catastrophic failure and mute the benefit of device and drug interventions. Finite Element (FE) simulations utilizing intravascular imaging OCT (Optical Coherence Tomography) are effective in defining physiological stress distributions. However, creating 3D FE simulations of coronary arteries from OCT images is challenging to fully automate given OCT frame sparsity, limited materi

SUBMITTER: Straughan R 

PROVIDER: S-EPMC10528179 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature