A scoping review of how early-stage knee osteoarthritis has been defined.

ABSTRACT:

Background

Early-stage knee osteoarthritis (KOA) classification criteria will enable consistent identification and trial recruitment of individuals with knee osteoarthritis (OA) at an earlier stage of the disease when interventions may be more effective. Toward this goal, we identified how early-stage KOA has been defined in the literature.

Methods

We performed a scoping literature review in PubMed, EMBASE, Cochrane, and Web of Science, including human studies where early-stage KOA was included as a study population or outcome. Extracted data included demographics, symptoms/history, examination, laboratory, imaging, performance-based measures, gross inspection/histopathologic domains, and the components of composite early-stage KOA definitions.

Results

Of 6142 article

SUBMITTER: Liew JW 

PROVIDER: S-EPMC10528892 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature