Ontology highlight
ABSTRACT:
SUBMITTER: Sureshchandra S
PROVIDER: S-EPMC10528932 | biostudies-literature | 2023 Jul
REPOSITORIES: biostudies-literature
Sureshchandra Suhas S Doratt Brianna M BM True Heather H Mendoza Norma N Rincon Monica M Marshall Nicole E NE Messaoudi Ilhem I
Cell reports 20230710 7
Leukocyte diversity of the first-trimester maternal-fetal interface has been extensively described; however, the immunological landscape of the term decidua remains poorly understood. We therefore profiled human leukocytes from term decidua collected via scheduled cesarean delivery. Relative to the first trimester, our analyses show a shift from NK cells and macrophages to T cells and enhanced immune activation. Although circulating and decidual T cells are phenotypically distinct, they demonstr ...[more]