Incidence of and Risk Factors for Cataract in Anterior Uveitis.

ABSTRACT:

Purpose

To estimate the incidence/risk factors for cataract in noninfectious anterior uveitis.

Design

Retrospective multicenter cohort study (6 US tertiary uveitis sites, 1978-2010).

Methods

Data were harvested by trained expert reviewers, using protocol-driven review of experts' charts. We studied cataract incidence-newly reduced visual acuity worse than 20/40 attributed to cataract; or incident cataract surgery-in 3923 eyes of 2567 patients with anterior uveitis.

Results

Cataract developed in 507 eyes (54/1000 eye-years, 95% CI 49-59). Time-updated risk factors associated with cataract included older age (≥65 vs <18 years: adjusted hazard ratio [aHR] 5.04, 95% CI 3.04-8.33), higher anterior chamber cell grade (P(trend)=0.001), prior incisional glaucoma surger

SUBMITTER: Papaliodis GN 

PROVIDER: S-EPMC10528977 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature