Reinfection incidence and risk among people treated for recent hepatitis C virus infection.

ABSTRACT:

Objective

Reinfection poses a challenge to hepatitis C virus (HCV) elimination. This analysis assessed incidence of, and factors associated with reinfection among people treated for recent HCV (duration of infection <12 months).

Methods

Participants treated for recent HCV (primary infection or reinfection) in an international randomized trial were followed at 3-monthly intervals for up to 2 years to assess for reinfection. Reinfection incidence was calculated using person-time of observation. Factors associated with HCV reinfection were assessed using Cox proportional hazards regression analysis.

Results

Of 222 participants treated for recent HCV, 196 (62% primary infection, 38% reinfection) were included in the cohort at risk for reinfection, of whom 87% identified a

SUBMITTER: Martinello M 

PROVIDER: S-EPMC10529102 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature