Feasibility of Simultaneous Quantification of Myocardial and Renal Perfusion With Cardiac Positron Emission Tomography.

ABSTRACT:

Background

Given the central importance of cardiorenal interactions, mechanistic tools for evaluating cardiorenal physiology are needed. In the heart and kidneys, shared pathways of neurohormonal activation, hypertension, and vascular and interstitial fibrosis implicate the relevance of systemic vascular health. The availability of a long axial field of view positron emission tomography (PET)/computed tomography (CT) system enables simultaneous evaluation of cardiac and renal blood flow.

Methods

This study evaluated the feasibility of quantification of renal blood flow using data acquired during routine, clinically indicated ¹³N-ammonia myocardial perfusion PET/CT. Dynamic PET image data were used to calculate renal blood flow. Reproducibility was assessed by the

SUBMITTER: Brown JM 

PROVIDER: S-EPMC10529360 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature