Geographical Patterns and Risk Factor Association of Cardio-Oncology Mortality in the United States.

ABSTRACT: Cardio-oncology mortality (COM) is a complex issue that is compounded by multiple factors that transcend a depth of socioeconomic, demographic, and environmental exposures. Although metrics and indexes of vulnerability have been associated with COM, advanced methods are required to account for the intricate intertwining of associations. This cross-sectional study utilized a novel approach that combined machine learning and epidemiology to identify high-risk sociodemographic and environmental factors linked to COM in United States counties. The study consisted of 987,009 decedents from 2,717 counties, and the Classification and Regression Trees model identified 9 county socio-environmental clusters that were closely associated with COM, with a 64.1% relative increase across the spectrum. Th

SUBMITTER: Motairek I 

PROVIDER: S-EPMC10529631 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature