Metal Messengers: Communication in the Bacterial World through Transition-Metal-Sensing Two-Component Systems.

ABSTRACT: Bacteria survive in highly dynamic and complex environments due, in part, to the presence of systems that allow the rapid control of gene expression in the presence of changing environmental stimuli. The crosstalk between intra- and extracellular bacterial environments is often facilitated by two-component signal transduction systems that are typically composed of a transmembrane histidine kinase and a cytosolic response regulator. Sensor histidine kinases and response regulators work in tandem with their modular domains containing highly conserved structural features to control a diverse array of genes that respond to changing environments. Bacterial two-component systems are widespread and play crucial roles in many important processes, such as motility, virulence, chemotaxis, and even t

SUBMITTER: Paredes A 

PROVIDER: S-EPMC10530140 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature