Patient level factors increase risk of acute kidney disease in hospitalized children with acute kidney injury.

ABSTRACT:

Background

Studies in adults have shown that persistent kidney dysfunction ≥7-90 days following acute kidney injury (AKI), termed acute kidney disease (AKD), increases chronic kidney disease (CKD) and mortality risk. Little is known about the factors associated with the transition of AKI to AKD and the impact of AKD on outcomes in children. The aim of this study is to evaluate risk factors for progression of AKI to AKD in hospitalized children and to determine if AKD is a risk factor for CKD.

Methods

Retrospective cohort study of children age ≤18 years admitted with AKI to all pediatric units at a single tertiary-care children's hospital between 2015 and 2019. Exclusion criteria included insufficient serum creatinine values to evaluate for AKD, chronic dialysis, or previous

SUBMITTER: Patel M 

PROVIDER: S-EPMC10530194 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature