A prospective study of severe irritability in youths: 2- and 4-year follow-up.

ABSTRACT:

Background

Severe, chronic irritability is receiving increased research attention, and is the cardinal symptom of a new diagnostic category, disruptive mood dysregulation disorder (DMDD). Although data from epidemiological community samples suggest that childhood chronic irritability predicts unipolar depression and anxiety in adulthood, whether these symptoms are stable and cause ongoing clinical impairment is unknown. The present study presents 4-year prospective and longitudinal diagnostic and impairment data on a clinical sample of children selected for symptoms of severe irritability (operationalized as severe mood dysregulation [SMD]).

Methods

Youth meeting criteria for SMD (n = 200) were evaluated at baseline using standard diagnostic methods. Two-year (n = 78) and 4-

SUBMITTER: Deveney CM 

PROVIDER: S-EPMC10530700 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature