Proteomics-Based Approach for Detailing the Allergenic Profile of Cannabis Chemotypes.

ABSTRACT: Allergic sensitization to cannabis is an emerging public health concern and is difficult to clinically establish owing to lack of standardized diagnostic approaches. Attempts to develop diagnostic tools were largely hampered by the Schedule I restrictions on cannabis, which limited accessibility for research. Recently, however, hemp was removed from the classified list, and increased accessibility to hemp allows for the evaluation of its practical clinical value for allergy diagnosis. We hypothesized that the proteomic profile is preserved across different cannabis chemotypes and that hemp would be an ideal source of plant material for clinical testing. Using a proteomics-based approach, we examined whether distinct varieties of cannabis plant contain relevant allergens of cannabis. Cannab

SUBMITTER: Loblundo C 

PROVIDER: S-EPMC10531008 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature