Effects of Denture Treatment on Salivary Metabolites: A Pilot Study.

ABSTRACT: Symptoms of oral discomfort such as dry mouth are common in older people wearing dentures. Such symptoms are mainly treated symptomatically. Many of these symptoms are related to saliva, and associations with salivary volume have been reported. Although denture treatment improves symptoms by increasing the amount of saliva, the effects on salivary components remain unclear. This study aimed to investigate the effects of denture treatment on salivary metabolite changes based on salivary metabolome analyses. We enrolled 21 patients requiring denture treatment. At the first visit, and after completion of denture treatment, saliva outflow was measured under resting and stimulated conditions, samples for salivary metabolite analysis were collected, and masticatory efficiency was tested. In all

SUBMITTER: Ichigaya N 

PROVIDER: S-EPMC10531179 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature