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The association of self-reported symptoms of central sensitization and sleep disturbances in neuropathic pain.


ABSTRACT:

Introduction

Patients with neuropathic pain (NP) report a higher impairment of quality of life and sleep than patients with chronic pain without neuropathic characteristics. These include somatosensory peculiarities like allodynia, a surrogate marker for central sensitization.

Objectives

This study aimed to investigate the relation between symptoms of central sensitization and sleep disturbances in patients with NP.

Methods

Within this cross-sectional study, data sets of 3339 patients with chronic NP syndromes (painful diabetic polyneuropathy, n = 543; postherpetic neuralgia, n = 1480) or complex regional pain syndromes (CRPS, n = 1316) were analyzed. Neuropathic pain symptoms were assessed with the painDETECT questionnaire (PD-Q), depression with the Patient Health Q

SUBMITTER: Sachau J 

PROVIDER: S-EPMC10531265 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature