Hylin-a1: A Pan-Inhibitor against Emerging and Re-Emerging Respiratory Viruses.

ABSTRACT: Pandemic and epidemic outbreaks of respiratory viruses are a challenge for public health and social care system worldwide, leading to high mortality and morbidity among the human populations. In light of the limited efficacy of current vaccines and antiviral drugs against respiratory viral infections and the emergence and re-emergence of new viruses, novel broad-spectrum antiviral drugs are needed for the prevention and treatment of these infections. Antimicrobial peptides with an antiviral effect, also known as AVPs, have already been reported as potent inhibitors of viral infections by affecting different stages of the virus lifecycle. In the present study, we analyzed the activity of the AVP Hylin-a1, secreted by the frog Hypsiboas albopunctatus, against a wide range of respirato

SUBMITTER: Chianese A 

PROVIDER: S-EPMC10531407 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature