Equivalent Survival between Gastric Large-Cell Neuroendocrine Carcinoma and Gastric Small-Cell Neuroendocrine Carcinoma.

ABSTRACT:

Background

According to the 2019 World Health Organization (WHO) classification of gastric neuroendocrine neoplasms, gastric neuroendocrine carcinoma (GNEC) can be further divided into gastric large-cell neuroendocrine carcinoma (GLNEC) and gastric small-cell neuroendocrine carcinoma (GSNEC). Whether the prognoses of the two types have a discrepancy has long been disputed.

Method

We collected patients diagnosed with GLNEC or GSNEC in the National Cancer Center of China between January 2000 and December 2020. The characteristics and survival outcomes were compared between the two groups. We further verified our conclusion using the SEER dataset.

Results

A total of 114 GNEC patients, including 82 patients with GLNEC and 32 patients with GSNEC, have completed treatment i

SUBMITTER: Li Z 

PROVIDER: S-EPMC10531653 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature