ANRIL rs4977574 Gene Polymorphism in Women with Recurrent Pregnancy Loss.

ABSTRACT:

Background

ANRIL rs4977574 gene polymorphism has been associated with arterial thrombosis and cardiovascular disease development. ANRIL rs4977574 gene polymorphism could also be associated with recurrent pregnancy loss (RPL) since there is increasing evidence in favor of a potential shared pathophysiological mechanism with cardiovascular disease, potentially through arterial thrombosis. This study's goal is to investigate the differences in ANRIL rs4977574 gene polymorphism between women with and without RPL, if any, as well as a potential association with the number of pregnancy losses.

Methods

DNA was isolated from peripheral blood samples, and the sequence containing the polymorphism of interest was amplified with PCR. Results were visualized under UV

SUBMITTER: Cherouveim P 

PROVIDER: S-EPMC10531795 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature