Advanced Anterior Eye Segment Imaging for Ichthyosis.

ABSTRACT: The purpose of this study was to describe ocular surface and anterior eye segment findings in various types of ichthyoses.

Methods

This was a single-center prospective observational study. The study group consisted of five patients (P1-P5) aged 13-66 years. Multimodal imaging was performed, including slit-lamp examinations, swept-source optical coherence tomography (SS-OCT), and in vivo confocal microscopy (IVCM).

Results

All patients were diagnosed with moderate-to-severe dry eye disease (DED). The corneas showed a significant pattern of irregularity, with a significant difference between the corneal thickness at the apex (CAT) and the corneal thinnest thickness (CTT), exceeding 375 µm. Three patients were diagnosed with ectasia patterns based on SS-OCT. All patients showed

SUBMITTER: Micinska A 

PROVIDER: S-EPMC10532152 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature