Identification of Novel Glycans in the Mucus Layer of Shark and Skate Skin.

ABSTRACT: The mucus layer covering the skin of fish has several roles, including protection against pathogens and mechanical damage. While the mucus layers of various bony fish species have been investigated, the composition and glycan profiles of shark skin mucus remain relatively unexplored. In this pilot study, we aimed to explore the structure and composition of shark skin mucus through histological analysis and glycan profiling. Histological examination of skin samples from Atlantic spiny dogfish (Squalus acanthias) sharks and chain catsharks (Scyliorhinus retifer) revealed distinct mucin-producing cells and a mucus layer, indicating the presence of a functional mucus layer similar to bony fish mucus albeit thinner. Glycan profiling using liquid chromatography-electrospray ionizat

SUBMITTER: Bachar-Wikstrom E 

PROVIDER: S-EPMC10532229 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature