Choroideremia: The Endpoint Endgame.
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ABSTRACT:
SUBMITTER: Abdalla Elsayed MEA
PROVIDER: S-EPMC10532430 | biostudies-literature | 2023 Sep
REPOSITORIES: biostudies-literature
Publications
Choroideremia: The Endpoint Endgame.
Abdalla Elsayed Maram E A MEA Taylor Laura J LJ Josan Amandeep S AS Fischer M Dominik MD MacLaren Robert E RE
International journal of molecular sciences 20230920 18
Choroideremia is an X-linked retinal degeneration resulting from the progressive, centripetal loss of photoreceptors and choriocapillaris, secondary to the degeneration of the retinal pigment epithelium. Affected individuals present in late childhood or early teenage years with nyctalopia and progressive peripheral visual loss. Typically, by the fourth decade, the macula and fovea also degenerate, resulting in advanced sight loss. Currently, there are no approved treatments for this condition. G ...[more]
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