Light-enabled deracemization of cyclopropanes by Al-salen photocatalysis.

ABSTRACT: Privileged chiral catalysts-those that share common structural features and are enantioselective across a range of reactions-continue to transform the chemical-research landscape¹. In recent years, new reactivity modes have been achieved through excited-state catalysis, processes activated by light, but it is unclear if the selectivity of ground-state privileged catalysts can be matched. Although the interception of photogenerated intermediates by ground-state cycles has partially addressed this challenge², single, chiral photocatalysts that simultaneously regulate reactivity and selectivity are conspicuously scarce³. So far, precision donor-acceptor recognition motifs remain crucial in enantioselective photocatalyst design⁴. Here we show that ch

SUBMITTER: Onneken C 

PROVIDER: S-EPMC10533403 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature