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ABSTRACT: Background
Trunk inclination from semirecumbent head-upright to supine-flat positioning reduces driving pressure and increases respiratory system compliance in patients with acute respiratory distress syndrome (ARDS). These effects are associated with an improved ventilatory ratio and reduction in the partial pressure of carbon dioxide (PaCO2). However, these physiological effects have not been completely studied, and their mechanisms have not yet been elucidated. Therefore, this study aimed to evaluate the effects of a change in trunk inclination from semirecumbent (45°) to supine-flat (10°) on physiological dead space and ventilation distribution in different lung regions.Results
Twenty-two ARDS patients on pressure-controlled ventilation underwent three 60-min
SUBMITTER: Benites MH
PROVIDER: S-EPMC10533449 | biostudies-literature | 2023 Sep
REPOSITORIES: biostudies-literature