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A meta-analytic review of the impact of ADHD medications on anxiety and depression in children and adolescents.


ABSTRACT: Anxiety and depression are listed as common side effects for medications licensed for treating ADHD in children and adolescents. This meta-analytic review of randomised controlled trials aimed to explore the effect of medications on symptoms of anxiety and depression in children and adolescents with ADHD. A meta-analytic review of ADHD drug trials in children and adolescents was conducted. Random effects meta-analyses were conducted on anxiety and depression outcomes measured by validated psychological scales or side effect rating scales. Only 11% of eligible trials in this review reported anxiety and/or depression as an outcome or side effect, limiting the conclusions of the meta-analyses. Relative to placebo control, no significant effect of medication was found for symptoms of anxiety o

SUBMITTER: Bryant A 

PROVIDER: S-EPMC10533622 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature