Treatment of metastatic squamous cell carcinoma arising in sacrococcygeal pilonidal sinus: a case report series.

ABSTRACT:

Background

Squamous cell carcinoma (SCC) arising in a sacrococcygeal pilonidal sinus is rare, with cases of metastatic disease being even rarer. Among published cases, almost none have reported on systemic treatment.

Objective

This disease has a poorer prognosis than other forms of cutaneous SCC; therefore, our objective is to shed some light on the treatment of metastatic disease.

Methods

We present a series of nine cases treated at a single center, four of whom received systemic treatment. Additionally, other previously reported cases of metastatic disease are included in an attempt to draw stronger conclusions.

Results

Four patients were treated under several treatment regimens, with a median progression-free survival of only 2 months and two instances of pa

SUBMITTER: Soria Rivas A 

PROVIDER: S-EPMC10534040 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature