Reporting of Observational Studies Explicitly Aiming to Emulate Randomized Trials: A Systematic Review.

ABSTRACT:

Importance

Observational (nonexperimental) studies that aim to emulate a randomized trial (ie, the target trial) are increasingly informing medical and policy decision-making, but it is unclear how these studies are reported in the literature. Consistent reporting is essential for quality appraisal, evidence synthesis, and translation of evidence to policy and practice.

Objective

To assess the reporting of observational studies that explicitly aimed to emulate a target trial.

Evidence review

We searched Medline, Embase, PsycINFO, and Web of Science for observational studies published between March 2012 and October 2022 that explicitly aimed to emulate a target trial of a health or medical intervention. Two reviewers double-screened and -extracted data on study charact

SUBMITTER: Hansford HJ 

PROVIDER: S-EPMC10534275 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature