Recombination in Bacterial Genomes: Evolutionary Trends.

ABSTRACT: Bacterial organisms have undergone homologous recombination (HR) and horizontal gene transfer (HGT) multiple times during their history. These processes could increase fitness to new environments, cause specialization, the emergence of new species, and changes in virulence. Therefore, comprehensive knowledge of the impact and intensity of genetic exchanges and the location of recombination hotspots on the genome is necessary for understanding the dynamics of adaptation to various conditions. To this end, we aimed to characterize the functional impact and genomic context of computationally detected recombination events by analyzing genomic studies of any bacterial species, for which events have been detected in the last 30 years. Genomic loci where the transfer of DNA was detected pertained

SUBMITTER: Shikov AE 

PROVIDER: S-EPMC10534446 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature