Prefrailty, impairment in physical function, and risk of incident heart failure among older adults.

ABSTRACT:

Objective

Evaluate the association between prefrailty and the risk of heart failure (HF) among older adults.

Design, setting, and participants

This prospective, community-based cohort study included participants from the Atherosclerotic Risk in Communities study who underwent detailed frailty assessment using Fried Criteria and physical function assessment using the Short Performance Physical Battery (SPPB) score. Individuals with prevalent HF and frailty were excluded.

Main outcomes and measures

Adjusted association between prefrailty (vs robust), physical function measures (SPPB score, grip strength, and gait speed), and incident HF (overall and HF subtypes, HF with reduced [HFrEF, EF < 50%] and preserved ejection fraction [HFpEF]) were assessed using Cox proportion

SUBMITTER: Segar MW 

PROVIDER: S-EPMC10535362 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature