Suprachoroidal Injection: A Novel Approach for Targeted Drug Delivery.

ABSTRACT: Treating posterior segment and retinal diseases poses challenges due to the complex structures in the eye that act as robust barriers, limiting medication delivery and bioavailability. This necessitates frequent dosing, typically via eye drops or intravitreal injections, to manage diseases, often leading to side effects with long-term use. Suprachoroidal injection is a novel approach for targeted drug delivery to the posterior segment. The suprachoroidal space is the region between the sclera and the choroid and provides a potential route for minimally invasive medication delivery. Through a more targeted delivery to the posterior segment, this method offers advantages over other routes of administration, such as higher drug concentrations, increased bioavailability, and prolonged duration

SUBMITTER: Wu KY 

PROVIDER: S-EPMC10535603 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature