Acinetobacter baumannii IC2 and IC5 Isolates with Co-Existing bla_OXA-143-like and bla_OXA-72 and Exhibiting Strong Biofilm Formation in a Mexican Hospital.

ABSTRACT: Acinetobacter baumannii is an opportunistic pathogen responsible for healthcare-associated infections (HAIs) and outbreaks. Antimicrobial resistance mechanisms and virulence factors allow it to survive and spread in the hospital environment. However, the molecular mechanisms of these traits and their association with international clones are frequently unknown in low- and middle-income countries. Here, we analyze the phenotype and genotype of seventy-six HAIs and outbreak-causing A. baumannii isolates from a Mexican hospital over ten years, with special attention to the carbapenem resistome and biofilm formation. The isolates belonged to the global international clone (IC) 2 and the Latin America endemic IC5 and were predominantly extensively drug-resistant (XDR). Oxacillinas

SUBMITTER: Moreno-Manjon J 

PROVIDER: S-EPMC10536109 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature