Epidemiological Characterisation of bla_NDM-Positive Enterobacterales from Food-Producing Animal Farms in Southwest China.

ABSTRACT: Carbapenems are atypical β-lactam antibiotics with a broade antibacterial spectrum and strong antibacterial activity; however, the emergence and spread of carbapenemases have led to a decline in their effectiveness. New Delhi metallo-β-lactamase (NDM) is an important carbapenemase that has attracted widespread attention and poses a major threat to public health. To investigate the epidemiological characteristics of bla_NDM in swine and chicken farms in southwestern China, we isolated 102 bla_NDM-positive Enterobacterales strains from 18 farms in Sichuan and Yunnan provinces in 2021, with Escherichia coli and Klebsiella spp. being the main reservoirs of bla_NDM, variant bla_NDM-5 being the most prevalen

SUBMITTER: Wen R 

PROVIDER: S-EPMC10536151 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature