Ethno-demographic disparities in humoral responses to the COVID-19 vaccine among healthcare workers.

ABSTRACT: The COVID-19 pandemic had a profound impact on global health, but rapid vaccine administration resulted in a significant decline in morbidity and mortality rates worldwide. In this study, we sought to explore the temporal changes in the humoral immune response against SARS-CoV-2 healthcare workers (HCWs) in Augusta, GA, USA, and investigate any potential associations with ethno-demographic features. Specifically, we aimed to compare the naturally infected individuals with naïve individuals to understand the immune response dynamics after SARS-CoV-2 vaccination. A total of 290 HCWs were included and assessed prospectively in this study. COVID status was determined using a saliva-based COVID assay. Neutralizing antibody (NAb) levels were quantified using a chemiluminescent immunoassay system

SUBMITTER: Ahluwalia P 

PROVIDER: S-EPMC10536788 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature