Genetic analysis of 42 Y-STR loci in Han and Manchu populations from the three northeastern provinces in China.

ABSTRACT:

Background

Y-STR polymorphisms are useful in tracing genealogy and understanding human origins and migration history. This study aimed to fill a knowledge gap in the genetic diversity, structure, and haplogroup distribution of the Han and Manchu populations from the three northeastern provinces in China (Liaoning, Jilin, and Heilongjiang).

Methods

A total of 1,048 blood samples were collected from unrelated males residing in Dalian. Genotyping was performed using the AGCU Y37 + 5 Amplification Kit, and the genotype data were analyzed to determine allele and haplotype frequencies, genetic and haplotype diversity, discrimination capacity, and haplotype match probability. Population pairwise genetic distances (F_st) were calculated to compare the genetic relationships

SUBMITTER: Song W 

PROVIDER: S-EPMC10537175 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature