Metformin in Gestational Diabetes Mellitus: To Use or Not to Use, That Is the Question.

ABSTRACT: In recent years, there has been a dramatic increase in the number of pregnancies complicated by gestational diabetes mellitus (GDM). GDM occurs when maternal insulin resistance develops and/or progresses during gestation, and it is not compensated by a rise in maternal insulin secretion. If not properly managed, this condition can cause serious short-term and long-term problems for both mother and child. Lifestyle changes are the first line of treatment for GDM, but if ineffective, insulin injections are the recommended pharmacological treatment choice. Some guidance authorities and scientific societies have proposed the use of metformin as an alternative pharmacological option for treating GDM, but there is not yet a unanimous consensus on this. Although the use of metformin appears to be

SUBMITTER: Tocci V 

PROVIDER: S-EPMC10537239 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature