Postoperative Opioid Prescribing and New Persistent Opioid Use: The Risk of Excessive Prescribing.

ABSTRACT:

Objective

Evaluate the association between postoperative opioid prescribing and new persistent opioid use.

Summary background data

Opioid-nave patients who develop new persistent opioid use after surgery are at increased risk of opioid-related morbidity and mortality. However, the extent to which postoperative opioid prescribing is associated with persistent postoperative opioid use is unclear.

Methods

Retrospective study of opioid-naïve adults undergoing surgery in Michigan from 1/1/2017 to 10/31/2019. Postoperative opioid prescriptions were identified using a statewide clinical registry and prescription fills were identified using Michigan's prescription drug monitoring program. The primary outcome was new persistent opioid use, defined as filling at least 1 opioid

SUBMITTER: Howard R 

PROVIDER: S-EPMC10537242 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature