First Detection and Molecular Characterization of Pseudomonas aeruginosa bla_NDM-1 ST308 in Greece.

ABSTRACT: The objective of the present study is to report the detection and the molecular characterization of nine bla_NDM-1-positive Pseudomonas aeruginosa isolates, all of which belonged to the epidemic high-risk international clone ST308, and all were isolated from patients in a tertiary care hospital in Central Greece from May to July 2023.The isolates were characterized by whole genome sequencing to obtain multi-locus sequencing typing (MLST) and identify the bla_NDM1-environment and resistome and virulence genes content. In silico MLST analysis showed that all isolates belonged to the high-risk ST308 international clone. All strains possessed 22 different genes, encoding resistance to various antimicrobial agents. Whole genome sequencing revealed that t

SUBMITTER: Tsilipounidaki K 

PROVIDER: S-EPMC10537375 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature