Effects of Bovine Lactoferrin on the Maintenance of Respiratory and Systemic Physical Conditions in Healthy Adults-A Randomized, Double-Blind, Placebo-Controlled Trial.

ABSTRACT:

Objectives

We investigated the effects of bovine lactoferrin (LF) on the maintenance of the respiratory and systemic physical conditions.

Methods

A randomized, double-blind, placebo-controlled trial was conducted. Healthy adults at Kyushu University of Health and Welfare ingested a placebo or bovine LF (200 mg/day) for 12 weeks. The primary endpoints were the total respiratory and systemic symptom scores. The secondary endpoint was the activity of plasmacytoid dendritic cells (pDCs) in peripheral blood.

Results

A total of 157 subjects were randomized (placebo, n = 79; LF, n = 78), of whom, 12 dropped out. The remaining 145 participants were included in the full analysis set (placebo group, n = 77; LF group, n = 68). The total scores for res

SUBMITTER: Oda H 

PROVIDER: S-EPMC10537451 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature