Prophylactic platelet transfusion response in critically ill patients: a prospective multicentre observational study.

ABSTRACT:

Background

Response to prophylactic platelet transfusion is suspected to be inconsistent in critically ill patients questioning how to optimize transfusion practices. This study aimed to describe prophylactic platelet transfusion response, to identify factors associated with a suboptimal response, to analyse the correlation between corrected count increment and platelet count increment and to determine the association between poor platelet transfusion response and clinical outcomes.

Methods

This prospective multicentre observational study recruited patients who received at least one prophylactic platelet transfusion in one of the nine participating intensive care units for a period up to 16 months. Poor platelet transfusion response was defined as a corrected count increment

SUBMITTER: Reizine F 

PROVIDER: S-EPMC10537531 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature