Association of Vitamin D Genetic Risk Score with Noncommunicable Diseases: A Systematic Review.

ABSTRACT: Background and Aims: The genetic risk score (GRS) is an important tool for estimating the total genetic contribution or susceptibility to a certain outcome of interest in an individual, taking into account their genetic risk alleles. This study aims to systematically review the association between the GRS of low vitamin D with different noncommunicable diseases/markers. Methods: The article was first registered in PROSPERO CRD42023406929. PubMed and Embase were searched from the time of inception until March 2023 to capture all the literature related to the vitamin D genetic risk score (vD-GRS) in association with noncommunicable diseases. This was performed using comprehensive search terms including "Genetic Risk Score" OR "Genetics risk assessment" OR "Genome-wide risk scor

SUBMITTER: Almaghrbi H 

PROVIDER: S-EPMC10537716 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature