Glutamine synthetase and GlnR regulate nitrogen metabolism in Paenibacillus polymyxa WLY78.

ABSTRACT: Paenibacillus polymyxa WLY78, a N₂-fixing bacterium, has great potential use as a biofertilizer in agriculture. Recently, we have revealed that GlnR positively and negatively regulates the transcription of the nif (nitrogen fixation) operon (nifBHDKENXhesAnifV) in P. polymyxa WLY78 by binding to two loci of the nif promoter according to nitrogen availability. However, the regulatory mechanisms of nitrogen metabolism mediated by GlnR in the Paenibacillus genus remain unclear. In this study, we have revealed that glutamine synthetase (GS) and GlnR in P. polymyxa WLY78 play a key role in the regulation of nitrogen metabolism. P. polymyxa GS (encoded by glnA within glnRA) and GS1 (encoded by glnA1

SUBMITTER: Zhao X 

PROVIDER: S-EPMC10537745 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature