Statins exposure and acute pancreatitis: a retrospective cohort study using a large national insurance database.

ABSTRACT:

Objectives

The association between the use of statins and the incidence of acute pancreatitis (AP) has yielded inconsistent findings. While statins have been implicated as an aetiology for drug-induced pancreatitis, more recent studies have found statin use is associated with a reduced risk of pancreatitis. We sought to examine the association between the use of any statin medications and the risk of AP using large real-world data.

Design

All data were collected retrospectively, but individuals were prospectively followed forward in time to determine the outcome of interest using International Classification of Diseases, 10th Revision, Clinical Modification codes indicating a diagnosis of AP. A stratified Cox proportional hazards regression model was conducted to examine the

SUBMITTER: Ba DM 

PROVIDER: S-EPMC10537853 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature