The effect of Shengmai injection in patients with coronary heart disease in real world and its personalized medicine research using machine learning techniques.

ABSTRACT: Objective: Shengmai injection is a common treatment for coronary heart disease. The accurate dose regimen is important to maximize effectiveness and minimize adverse reactions. We aim to explore the effect of Shengmai injection in patients with coronary heart disease based on real-world data and establish a personalized medicine model using machine learning and deep learning techniques. Methods: 211 patients were enrolled. The length of hospital stay was used to explore the effect of Shengmai injection in a case-control study. We applied propensity score matching to reduce bias and Wilcoxon rank sum test to compare results between the experimental group and the control group. Important variables influencing the dose regimen of Shengmai injection were screened by XGBoost. A pe

SUBMITTER: Ma J 

PROVIDER: S-EPMC10537936 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature