Health-related quality of life associated with warfarin and direct oral anticoagulants in venous thromboembolism.

ABSTRACT:

Introduction

Venous thromboembolism (VTE) is commonly treated with oral anticoagulants, including warfarin or direct oral anticoagulants (DOACs). Although DOACs are associated with favorable treatment satisfaction, few studies have assessed whether quality of life differs between DOAC and warfarin users.

Materials and methods

We invited adults enrolled in two California-based integrated health care delivery systems and with a history of VTE between January 1, 2015 and June 30, 2018 to complete a survey on their experience with anticoagulants. Health-related quality of life (QOL) was assessed using the RAND 36-item Short Form Health Survey (SF-36), which measures QOL in 2 general component scores (physical and mental). We used multivariable linear regression to compare mean Q

SUBMITTER: Fang MC 

PROVIDER: S-EPMC10537975 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature